Selected inflammatory breast cancer research published in 2018
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An abstract is a brief summary of a research article, thesis, review, conference proceeding, or any in-depth analysis of a particular subject and is often used to help the reader quickly ascertain the paper’s purpose. The abstract can convey the main results and conclusions of a scientific article but the full text article must be consulted for details of the methodology, the full experimental results, and a critical discussion of the interpretations and conclusions.
The abstract below is edited for length. Read the free, complete article on PubMed Central.
Gutierrez Barrera AM., et al. (2018) BRCA mutations in women with inflammatory breast cancer. Cancer. 2018 Feb 1;124(3):466-474. doi: 10.1002/cncr.31069.
Inflammatory breast cancer (IBC) often affects women at a relatively young age. To the authors’ knowledge, the rate of BRCA variants among patients with IBC is not known. To determine the association between BRCA status and IBC, the authors evaluated its rate and compared the clinicopathologic characteristics of patients with IBC with those of patients with other breast cancers (non-IBC).
There was no clear association observed between BRCA pathogenic variants and IBC. However, among patients who tested positive for BRCA pathogenic variants, those with IBC were younger at the time of diagnosis compared with those with non-IBC breast cancers. However, among patients who tested positive for BRCA pathogenic variants, those with IBC were younger at the time of diagnosis compared with those with non-IBC breast cancers. This information could assist in targeting patients with specific preventive strategies based on their modifiable behavioral patterns.