Clinical characteristics and outcome of bone-only metastasis in inflammatory and noninflammatory breast cancer

Selected inflammatory breast cancer research published in 2015

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Kai, M., et al. (2015). Clinical characteristics and outcome of bone-only metastasis in inflammatory and noninflammatory breast cancers. Clinical Breast Cancer, 15(1), 37-42.

BACKGROUND:
Inflammatory breast cancer is a rare and aggressive presentation of breast cancer. Bone is a common metastatic site in breast cancer, and bone-only metastatic disease is clinically considered to have a better prognosis than visceral metastasis. However, bone-only metastasis in IBC (bone-only IBC) has not been compared with bone-only metastasis in non-IBC (bone-only non-IBC) in terms of clinical features and outcome. Because of the intrinsically aggressive nature of IBC, we hypothesized that bone-only IBC has a poorer prognosis than does bone-only non-IBC.
CONCLUSION:
Bone-only IBC has a poorer prognosis than does bone-only non-IBC, particularly in those with ER-positive tumors. We might need to consider more aggressive intervention (eg, chemotherapy) for IBC patients with ER-positive bone-only metastatic disease.

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