Inflammatory breast cancer: patterns of failure and the case for aggressive locoregional management

Selected inflammatory breast cancer research published in 2015

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Warren, L.E., et al. (2015). Inflammatory breast cancer: patterns of failure and the case for aggressive locoregional management. Annals of Surgical Oncology, 22(8), 2483-91. doi:10.1245/s10434-015-4469-4.

BACKGROUND:
Inflammatory breast cancer (IBC) is a rare and aggressive subtype. This study analyzes the patterns of failure in patients with IBC treated at our institution.
CONCLUSIONS:
For non-MET patients, LRR remains a problem despite trimodality therapy. More aggressive treatment is warranted. For MET patients, nearly 60% have LRPR with systemic therapy alone. Local therapy should be considered in the setting of metastatic disease to prevent potential morbidity of progressive local disease.

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