Metabolic characterization of inflammatory breast cancer with baseline FDG-PET/CT: relationship with pathologic response after neoadjuvant chemotherapy, receptor status, and tumor grade

Selected inflammatory breast cancer research published in 2018

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Jacene HA., et al. (2018) Metabolic Characterization of Inflammatory Breast Cancer With Baseline FDG-PET/CT: Relationship With Pathologic Response After Neoadjuvant Chemotherapy, Receptor Status, and Tumor Grade. Clinical Breast Cancer. doi: 10.1016/j.clbc.2018.11.010.

BACKGROUND:
The aim of this study was to determine if, in inflammatory breast cancer (IBC), baseline metabolic activity (maximum standardized uptake value [SUVmax]) of primary tumor and involved regional lymph nodes (IRLN) are prognostic markers of response after neoadjuvant systemic therapy (NAS).
CONCLUSION:
2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography/computed tomography provides prognostic information for newly diagnosed IBC. Larger studies are needed to confirm these findings and assess how such early information could affect treatment choices for IBC in the neoadjuvant setting.

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