Selected inflammatory breast cancer research published in 2011
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The abstract below is edited for length. Read the free complete article on PubMed Central.
Li, J., et al. (2011). Triple-negative subtype predicts poor overall survival and high locoregional relapse in inflammatory breast cancer. Oncologist, 16(12), 1675-83.
Numerous studies have demonstrated that expression of estrogen/progesterone receptor (ER/PR) and human epidermal growth factor receptor (HER)-2 is important for predicting overall survival (OS), distant relapse (DR), and locoregional relapse (LRR) in early and advanced breast cancer patients. However, these findings have not been confirmed for inflammatory breast cancer (IBC), which has different biological features than non-IBC.
TN disease is associated with worse OS, DR, and LRR outcomes in IBC patients, indicating the need for developing new locoregional and systemic treatment strategies for patients with this aggressive subtype.